Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: systematic review
نویسندگان
چکیده
منابع مشابه
Oral mucolytic drugs for exacerbations of chronic obstructive pulmonary disease: systematic review.
OBJECTIVE To assess the effects of oral mucolytics in adults with stable chronic bronchitis and chronic obstructive pulmonary disease. DESIGN Systematic review of randomised controlled trials that compared at least two months of regular oral mucolytic drugs with placebo. STUDIES Twenty three randomised controlled trials in outpatients in Europe and United States. MAIN OUTCOME MEASURES Exa...
متن کاملOral corticosteroids for exacerbations of chronic obstructive pulmonary disease.
Background. The role of oral corticosteroids in treating patients with exacerbations of chronic obstructive pulmonary disease (COPD) remains contentious. We assessed in a prospective, randomised, doubleblind, placebo-controlled trial the effects of oral corticosteroid therapy in patients with exacerbations of COPD requiring hospital admission. Methods. We recruited patients with non-acidotic ex...
متن کاملMucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease.
BACKGROUND Individuals with chronic bronchitis or chronic obstructive pulmonary disease (COPD) may suffer recurrent exacerbations with an increase in volume and/or purulence of sputum and any therapy that reduced the number of exacerbations would be useful. There is a marked difference between countries in terms of the prescribing of mucolytics depending on whether or not they are perceived to ...
متن کاملChronic Obstructive Pulmonary Disease Exacerbations
INTRODUCTION Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in the United States, accounting for approximately 110,000 deaths per year. COPD is a slowly progressive condition, with symptoms typically arising around age 50 to 60 years. As the U.S. population of current and former smokers ages, the prevalence of this disease is expected to climb [1]. More than 1...
متن کاملCorticosteroid therapy for patients with acute exacerbations of chronic obstructive pulmonary disease: a systematic review.
OBJECTIVE To determine whether systemic corticosteroids are of benefit to patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). METHODS An English-language search of MEDLINE (1966 to February 2002) and the Cochrane Library and a bibliographic review was performed to identify published clinical trials of systemic corticosteroid administration in acute exacerbations...
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ژورنال
عنوان ژورنال: BMJ
سال: 2001
ISSN: 0959-8138
DOI: 10.1136/bmj.322.7297.1271